Overview
Discover, engineer, optimize, and scale up your enzyme
Whether you’re looking for a biocatalyst to replace a chemical synthesis step, looking to improve your enzyme’s function, or aiming to lower your manufacturing costs, Ginkgo’s best-in-class capabilities empower your enzyme R&D.
Have a question or ready to start a project?
End-to-End Capabilities.
Unparalleled Scale.
From computational design to novel enzyme discovery to commercial scale-up, Ginkgo’s services enable the discovery, optimization, and production of enzymes for diverse applications.
Leverage Ginkgo’s proprietary gene database encompassing >2 billion genes and >8 million natural product gene clusters as well as our advanced machine learning tools, ultra high throughput automation, and proprietary bacterial and fungal production hosts to search through the vastness of biological design space to discover novel enzyme activities, optimize enzyme function, improve expression, and scale up manufacturing processes for enzyme production.

Discover New Enzymes

Discover New Enzymes
- Discover novel enzyme activity and identify starting points for further protein engineering by drawing from our incredibly broad database of proprietary and public genomic sequences
- Mine genome databases using our in-house computational tools to identify thousands of potential hits
- Leverage metagenomic screens to design around existing IP that would otherwise block your development
- Screen candidates using advanced ultra high throughput screening methods to identify unique enzymes with your desired activity
Optimize Enzyme Function & Stability

Optimize Enzyme Function & Stability
- Use a broad and constantly expanding toolkit of evolutionary, computational, and rational protein engineering approaches to iteratively improve catalytic activity, enzyme stability, specificity, and expression
- Dramatically improve your enzyme’s function by leveraging our platform’s supervised machine learning, powered by data from our ultra high throughput assays
Access Best-in-Class Production Hosts for Robust Expression

Access Best-in-Class Production Hosts for Robust Expression
- Express your enzyme in our proprietary bacterial and fungal hosts optimized for protein production, including next-generation methanol-free Pichia pastoris and low viscosity Aspergillus niger
- Leverage our deep strain engineering expertise to optimize enzyme expression in our high expression host strains, tailored to support optimal expression of your enzyme to reduce your production costs
Develop an Optimized Fermentation Process

Develop an Optimized Fermentation Process
- Use our fleet of hundreds of Sartorius Ambr® 250 bioreactors to automate design of experiments at lab scale to quickly develop fermentation processes with a proven record of transferring to commercial scale
Fermentation Scale Up, Process Design & Tech Transfer

Fermentation Scale Up, Process Design & Tech Transfer
- Access our fermentation capacity, ranging from Ginkgo’s fleet of ~300 Sartorius Ambr® 250 bioreactors to our vessels spanning 1, 5, 10, 30, and 3,000 L and all the way up to the 50,000 L scale with our manufacturing partners, including GMP production
- Optimize your downstream processing and purification methods
- Utilize Ginkgo’s thermal, physical, and chemical separation capabilities to purify a sample for further analysis, testing, or proof of concept
- Enjoy quick project starts thanks to Ginkgo’s incoming analytical technology transfer capabilities and ensure smooth tech transfers back to your team or to your manufacturing partner of choice
- Receive cost modeling and feasibility assessments from our team to inform your decision-making

Markets We Serve
Agriculture
Biopharmaceutical
Governments
Industrials
Nutrition & Wellness
…and many more!
Speak with Us
Start a project today.
We program cells—enabling you to grow the future of medicine, food, materials, and more.
Featured Projects & News
Speak to our team today to access more.
Agriculture
Biopharmaceutical
Governments
Industrials
Nutrition & Wellness
Virtual Event
Ginkgo
Cell Therapy Services
Learn about Ginkgo’s latest tech for cell therapy R&D, including recent data from our CAR screening platform.
We can help you discover novel CAR-T therapeutics, including candidates that are effective against solid tumors.