Biopharmaceutical

Overview

Unleash the full potential of your R&D team

Ginkgo’s services empower customers across all stages of the drug development pipeline, from discovery through manufacturing. Our world-class synthetic biology platform combines computational design and ultra high throughput genetic engineering and screening with expertise in process development and manufacturing scale-up. Ginkgo helps your R&D team develop more effective therapeutics and solve your greatest drug development challenges.

Get in touch with the Ginkgo team today to discuss your R&D challenges!

Harness biology’s full breadth
for therapeutics and vaccines.

From small molecule discovery and manufacturing to biologics, cell and gene therapy, RNA therapeutics and vaccines, and beyond, Ginkgo is your cell engineering partner. Our services enable discovery, optimization, and scale up for a wide range of therapeutics modalities. See below for a selection of our application areas and case studies.

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Select Application Areas

Biocatalysis & Biosynthesis for API Manufacturing

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Biocatalysis & Biosynthesis for API Manufacturing

  • Discover and optimize the activity, function, and manufacturing of enzymes to replace chemical synthesis steps

  • Leverage our metabolic engineering expertise to create sustainable production processes and supply chains for small molecule medicines via fermentation

  • Engineer production host organisms to optimize manufacturing processes

RNA Therapeutics & Vaccines

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RNA Therapeutics & Vaccines

  • Utilize proprietary assays and ultra high throughput screening to optimize the activity and stability of linear and circular RNA for enhanced function and tissue-specific expression and manufacture candidates in quantities ready for animal studies 

  • Optimize the activity and production of enzyme reagents used in RNA manufacturing and in vitro translation

  • Increase plasmid titer and optimize downstream processing yield to reduce manufacturing costs

Cell Therapies

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Cell Therapies

  • Design and screen large pooled combinatorial libraries of CAR domains to find the most effective design for improved persistence

  • Develop and optimize synthetic inducible promoters for expression and targeting of CAR therapies

  • Optimize construction of CAR-T, CAR-NK, and other cell types with iPSC genomic safe harbors

Gene Therapies

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Gene Therapies

  • Engineer viral capsids to develop gene therapies with enhanced tropism, reduced immunogenicity, and improved transduction efficiency

  • Engineer payloads with custom regulatory elements and inverted terminal repeats (ITRs) to improve efficiency and efficacy 

  • Design and optimize more productive cell lines and processes for efficient gene therapy production

Biologics Discovery & Manufacturing

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Biologics Discovery & Manufacturing

  • Design novel therapeutic proteins with high throughput assays for function and manufacturability

  • Optimize protein expression in microbial host cells for reduced manufacturing costs

Microbiome

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Microbiome

  • Use high throughput characterization to identify key gut microbiome strains and their modes of action

  • Develop living medicines through metabolic engineering and enzyme optimization

  • Create more effective microbiome therapies using ultra high throughput screening to evaluate impact of microbiome produced small molecules on immune system

And more…

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And more…

  • Discover natural products and gene editing systems using genome mining of proprietary sequence databases

  • Develop new modalities — talk to our team today!
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Speak with Us

Start a project today.

We program cells—enabling you to grow the future of medicine, materials, food, and more.

Contact Us
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What We Do

Featured Projects & News

Ginkgo is your end-to-end synthetic biology R&D partner. Browse a selection of our partner projects and case studies to explore how our services are being used across industries.

Speak to our team today to learn more.

Enzymes

Whether you’re looking for a biocatalyst to replace a chemical synthesis step, looking to improve your enzyme’s function, or aiming to lower your manufacturing costs, Ginkgo’s best-in-class enzyme capabilities empower your R&D.

Enzymes

Optimizing Crucial Drug Manufacturing of APIs with Merck

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Improving the Specificity and Activity of a Biocatalyst

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Enzyme Discovery Powered by Large Metagenomic Libraries

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Optimizing Enzyme Expression and Performance with Zymtronix

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Advancing Treatments for Orphan and Rare Diseases with Selecta Biosciences

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Improving the Manufacture of Biosynthetic Heparin with Optimvia

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Developing Water Quality Biosensors with FREDSense

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Investigational Synthetic Biotic Medicine for Homocystinuria with Synlogic

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Discovering Novel Live Biotherapeutics with Microba

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Developing High-Efficacy Adjuvants for Vaccines with SaponiQx

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New Platform Ventures: Launching Verb Biotics, Ayana Bio

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Developing Synthetic Biotics for Gout with Synlogic

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Accelerating Production of Essential Medicines with Antheia

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Optimizing the Brightness of Glowing Plants with Light Bio

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Proteins

Discover and synthesize novel functional proteins, optimize your protein production, or enhance processes to scale up your protein manufacturing: Ginkgo’s best-in-class protein capabilities empower your R&D.

Proteins

High Throughput Screening for Designing Novel CAR-T Cell Therapies

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Developing Next-Generation Gene Therapy Capsids with Selecta Biosciences

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Improving the Manufacture of Biosynthetic Heparin with Optimvia

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Optimizing Silk Protein Production with Bolt Threads

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Developing Water Quality Biosensors with FREDSense

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Engineering Living Biotherapeutics for Gastrointestinal Health with Tantu

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A New Modality of Medicine: Nucleic Acid Vaccines

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Metabolic Engineering

Leverage Ginkgo’s expertise in metabolic engineering and our foundry scale to program microorganisms to manufacture your molecule of interest.

Metabolic Engineering

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Unlocking the Potential of Expression Systems for Medicines with Novo Nordisk

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Aliquots

Optimizing Production of Biobased Speciality Chemicals with Lygos

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Producing Rare, Natural Ingredients with Givaudan

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Sustainable Beauty and Personal Care Products with Sumitomo Chemical

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Metabolic Engineering for Lower Cost Feedstocks

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Commercializing Cultured Ingredients with Robertet

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Celebrating Cronos Group’s First-of-a-Kind CBC Product

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Scaling Production of Cultured THCV with Cronos Group

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Ultra High Throughput Genome Engineering for the Production of Specialty Chemicals

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Accelerating Industrial Adoption of High-Performance Biomaterials with Cambium

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Biobased Alternatives to Synthetic Polymers with Bioweg

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Developing High-Efficacy Adjuvants for Vaccines with SaponiQx

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Developing Water Quality Biosensors with FREDSense

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Improving Production Efficiency for Vibrant Food Colors with Phytolon

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Optimizing the Brightness of Glowing Plants with Light Bio

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New Platform Ventures: Launching Verb Biotics, Ayana Bio

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Strain Optimization

Increase your titers, improve your strain’s robustness in harsh conditions, or evolve it to grow on more cost-effective inputs: Ginkgo’s best-in-class strain optimization services can help deliver on your goals.

Strain Optimization

Manufacturing Breakthrough for mRNA Raw Materials with Aldevron

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Strain Improvement for Sustainable Agriculture with Bayer

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Ginkgo Expands Agricultural Biologicals Division, Closes Deal with Bayer

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Optimizing Crucial Drug Manufacturing of APIs with Merck

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Colorful yeast in plate

Unlocking the Potential of Expression Systems for Medicines with Novo Nordisk

Learn more

Supporting COVID-19 mRNA Vaccine Development with Moderna

Learn more

Celebrating Cronos Group’s First-of-a-Kind CBC Product

Learn more

Ultra High Throughput Genome Engineering for the Production of Specialty Chemicals

Learn more

Accelerating Production of Essential Medicines with Antheia

Learn more

Biobased Alternatives to Synthetic Polymers with Bioweg

Learn more

Developing High-Efficacy Adjuvants for Vaccines with SaponiQx

Learn more

Developing Next-Generation Gene Therapy Capsids with Selecta Biosciences

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Engineering Bacteria for Cancer Patient Treatment with Prokarium

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A very fine illustration in green of an X-rayed T. rex with a bundle of E. coli in an inset circle and the word Sue written in cursive overlayed on top of everything

Developing Synthetic Biotics for Gout with Synlogic

Learn more

Developing Water Quality Biosensors with FREDSense

Learn more
Digital collage of live bacterial biotherapeutics

Discovering Novel Live Biotherapeutics with Microba

Learn more

Engineering Living Biotherapeutics for Gastrointestinal Health with Tantu

Learn more

Genes × Jeans: Accelerating Production of Sustainable Dyes with Huue

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Improving Production Efficiency for Vibrant Food Colors with Phytolon

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Improving the Manufacture of Biosynthetic Heparin with Optimvia

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Investigational Synthetic Biotic Medicine for Homocystinuria with Synlogic

Learn more

Optimizing Enzyme Expression and Performance with Zymtronix

Learn more
Aliquots

Optimizing Production of Biobased Speciality Chemicals with Lygos

Learn more

Optimizing Silk Protein Production with Bolt Threads

Learn more

New Platform Ventures: Launching Verb Biotics, Ayana Bio

Learn more

High Throughput Screening for Designing Novel CAR-T Cell Therapies

Learn more

Accelerating Industrial Adoption of High-Performance Biomaterials with Cambium

Learn more

Producing Rare, Natural Ingredients with Givaudan

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Process Design & Scale Up

Utilize Ginkgo’s best-in-class scale up, processing, and production services at bench, pilot, and commercial scales. Ginkgo’s capabilities enable and improve the scaled production of your product.

Process Design & Scale Up

Celebrating Cronos Group’s First-of-a-Kind CBC Product

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Ginkgo Expands Agricultural Biologicals Division, Closes Deal with Bayer

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Manufacturing Breakthrough for mRNA Raw Materials with Aldevron

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Supporting COVID-19 mRNA Vaccine Development with Moderna

Learn more

Scaling Production of Cultured THCV with Cronos Group

Learn more

Optimizing Crucial Drug Manufacturing of APIs with Merck

Learn more
Digital collage of live bacterial biotherapeutics

Discovering Novel Live Biotherapeutics with Microba

Learn more

Producing Rare, Natural Ingredients with Givaudan

Learn more

Scaled Production of Cultured CBG with Cronos Group

Learn more

Biobased Alternatives to Synthetic Polymers with Bioweg

Learn more

Developing High-Efficacy Adjuvants for Vaccines with SaponiQx

Learn more

Improving the Manufacture of Biosynthetic Heparin with Optimvia

Learn more

Launching Commercial Production of Cultured Cannabinoids with Cronos

Learn more

Optimizing Enzyme Expression and Performance with Zymtronix

Learn more

New Platform Ventures: Launching Verb Biotics, Ayana Bio

Learn more

Accelerating Industrial Adoption of High-Performance Biomaterials with Cambium

Learn more

Improving Production Efficiency for Vibrant Food Colors with Phytolon

Learn more

Strain Improvement for Sustainable Agriculture with Bayer

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Biosecurity

Biology-powered. Data-driven. People-centric. Ginkgo’s end-to-end platform provides the system and tools needed to prevent, detect, and respond to pathogens.

Biosecurity

Building a Global Bioradar System with Concentric by Ginkgo

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Tracking Pathogen Variants with Rwanda Biomedical Centre

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Developing Water Quality Biosensors with FREDSense

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Needle in a Haystack: Looking for Compounds to Treat COVID-19

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